piercingly, shrilly, frantically, desperately
Ребёнок истошно закричал.
The child screamed piercingly.
Пёс истошно завыл посреди ночи.
The dog let out a piercing howl in the middle of the night.
Она истошно звала на помощь во дворе.
She shouted desperately for help in the courtyard.
Ребёнок истошно закричал от боли.
The child screamed piercingly in pain.
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