piercingly, shrilly, frantically, desperately
Ребёнок истошно закричал.
The child screamed piercingly.
Она истошно звала на помощь во дворе.
She shouted desperately for help in the courtyard.
Пёс истошно завыл посреди ночи.
The dog let out a piercing howl in the middle of the night.
Ребёнок истошно закричал от боли.
The child screamed piercingly in pain.
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